Encap Drug Delivery

Abusolve - abuse deterrent formulations

Abusolve is a suite of formulation approaches used for controlled drugs products, which combine to minimize the risk of a potential abuser’s tampering with the dosage unit. This may be by directly injecting the product, powdering a mass or chemically extracting the active

Protect your controlled release formulations from being abused

Sustained release formulations contain high amounts of drug substance that need to be delivered over a period of time. These formulations tend to be abused or "treated" to liberate all of the drug for immediate absorption into the body to induce a high.

Abusolve technology allows the sustained release formulation to meet its controlled release targets but also deters the potential abuser from being able to extract the drug substance, due to the characteristics of the formulation.

  • High melting point excipients - Resists heating and injecting
  • Taste modifiers - Resists covert administration, snorting & dose dumping
  • Water insolubles - Resists extraction and drink adulteration
  • Waxy excipients - Resists snorting
  • Viscosity modifiers - Resists dissolution, injection and dose dumping
  • Low density excipients - Resists drink adulteration
  • Dyes - Resists adulteration

To find out more about Abusolve licensing opportunities, please contact us

 

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